THE SYNTHESIS OF RHODOPSIN FROM VITAMIN A , By GEORGE WALD AND RUTH HUBBARD
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چکیده
material is a single molecular species, rather than a mixture of the native and slightly modified pignments. Note added in pro9f: Since this account was written we have observed regenerations of 85 per cent in purified cattle rhodopsin, flooded with retinenel, and bleached for 1 minute in intense light. 11 Wald, G., Documenta Ophthal., 3, 94 (1949). 12 Shantz, E. M., Embree, N. D., Hodge, H. C., and Wills, J. H., J. Biol. Chem., 163, 455 (1946). 13 Millard, E. B., and McCann, W. S., J. Applied Physiol., 1, 807 (1949). 14 I am greatly indebted for this preparation to Dr. Edgar M. Shantz of the Research Laboratories of Distillation Products, Inc., of Rochester, New York. 16 Wald, G., Meyerhof Festschrift, Biochem. et Biophys. Acta, 4, 215 (1950). Based on a reaction discovered by Morton, R. A., Salah, M. K., and Stubbs, A. L., Biochem. J., 40, Proc. lix (1946). 16 Negelein, E., and Wulff, H.-J., Biochem. Z., 293, 351 (1937). Lutwak-Mann, C., Biochem. J., 32, 1364 (1938). We owe the basic information on aldehyde fixation to the studies of Carl Neuberg and his coworkers [cf. Neuberg, C., and Kobel, M., Biochem. Z., 188, 211 (1927)]. 17 Wald, G., and Hubbard, R., PROC. NATL. ACAD. SCI., 36, 92 102 (1950).
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